The findings, “Epigenetic differences in Normal colon cancer prevention research.
“There have always been questions about why things such as diet and obesity are independent risk factors for colon cancer,” said Carmen Sapienza, Professor of Pathology at the Fels Institute for Molecular Biology, authors major study. “This study shows how and why the high-fat diet is associated with colon cancer.”
“This food is changed on an insulin gene methylation pattern of a person so that they express different insulin pump out more than the body needs,” says Sapienza. “In people who have had colon cancer, metabolic pathways of glucose and insulin signaling pathway runs on a completely different level than people who do not have colon cancer.”
Sapienza said that cancer cells love insulin and studies have shown that tumor feeds of insulin. “Insulin is only supposed to be expressed in the pancreas, so having this extra insulin is bad,” he said.